Biotin-PEG4-allyl

Modify Date: 2024-01-10 20:51:49

Biotin-PEG4-allyl Structure
Biotin-PEG4-allyl structure
Common Name Biotin-PEG4-allyl
CAS Number 1643661-79-3 Molecular Weight 459.60
Density N/A Boiling Point N/A
Molecular Formula C21H37N3O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG4-allyl


Biotin-PEG4-allyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG4-allyl

 Biotin-PEG4-allyl Biological Activity

Description Biotin-PEG4-allyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C21H37N3O6S
Molecular Weight 459.60