Atorvastatin lactone

Modify Date: 2024-01-02 17:50:30

Atorvastatin lactone structure	Common Name	Atorvastatin lactone
	CAS Number	125995-03-1	Molecular Weight	540.625
	Density	1.2±0.1 g/cm3	Boiling Point	674.8±55.0 °C at 760 mmHg
	Molecular Formula	C₃₃H₃₃FN₂O₄	Melting Point	103-106ºC
	MSDS	N/A	Flash Point	361.9±31.5 °C

Use of Atorvastatin lactone

Atorvastatin lactone is a prodrug form of atorvastatin. Atorvastatin is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor[1].

Name	5-(4-fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-N,4-diphenyl-2-propan-2-ylpyrrole-3-carboxamide
Synonym	More Synonyms

Description	Atorvastatin lactone is a prodrug form of atorvastatin. Atorvastatin is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR) Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
References	[1]. Valesky RJ, et al. Automated enzyme inhibition assay method for the determination of atorvastatin-derived HMG-CoA reductase inhibitors in human plasma using radioactivity detection. J Pharmacol Toxicol Methods. 2008 Jan-Feb;57(1):61-9.

Density	1.2±0.1 g/cm3
Boiling Point	674.8±55.0 °C at 760 mmHg
Melting Point	103-106ºC
Molecular Formula	C₃₃H₃₃FN₂O₄
Molecular Weight	540.625
Flash Point	361.9±31.5 °C
Exact Mass	540.242432
PSA	80.56000
LogP	4.30
Vapour Pressure	0.0±2.2 mmHg at 25°C
Index of Refraction	1.617

RIDADR	UN 2811 6.1 / PGII
HS Code	2934999090

Precursor 9
CAS#:842163-03-5 (2R,4R)-1-[2-(4... CAS#:134523-00-5 Atorvastatin CAS#:581772-29-4 Atorvastatin Ac... CAS#:125971-86-0 tert-butyl 2-((...
CAS#:125971-96-2 Benzenebutanami... CAS#:340266-37-7 [R-(R,R)]-2-(... CAS#:125971-95-1 Atorvastatin Ac... CAS#:67-56-1 Methanol
CAS#:110862-44-7 α-[[2-(1,3-diox...
DownStream 1
CAS#:134523-01-6 Atorvastatin Sodium

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-(4-Fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-N,4-di(phenyl)-2-propan-2-ylpyrrole-3-carboxamide

Benzeneacetamide,a-cyano-4-methoxy

5-(4-Fluorophenyl)-1-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide

5-(4-Fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide

Atorvastatin lactone

1H-Pyrrole-3-carboxamide, 5-(4-fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-

4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide

Atorvastatin Impurity 23

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Atorvastatin lactone
Price: ￥766.0/1g ￥306.0/250mg ￥2736.0/5g
Purity: 95.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: 1044582 USP Atorvastatin Related Compound H
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Atorvastatin lactone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Atorvastatin lactone
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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