Osmundacetone

Modify Date: 2024-01-08 07:08:12

Osmundacetone Structure
Osmundacetone structure
Common Name Osmundacetone
CAS Number 123694-03-1 Molecular Weight 178.18500
Density 1.264g/cm3 Boiling Point 382.5ºC at 760mmHg
Molecular Formula C10H10O3 Melting Point 173-175ºC
MSDS N/A Flash Point 199.3ºC

 Use of Osmundacetone


(E)-Osmundacetone is the isomer of Osmundacetone. Osmundacetone significantly suppresses the phosphorylation of MAPKs, including JNK, ERK, and p38 kinases. Osmundacetone has a neuroprotective effect against oxidative stress[1].

 Names

Name 4-(3,4-dihydroxyphenyl)but-3-en-2-one
Synonym More Synonyms

 Osmundacetone Biological Activity

Description (E)-Osmundacetone is the isomer of Osmundacetone. Osmundacetone significantly suppresses the phosphorylation of MAPKs, including JNK, ERK, and p38 kinases. Osmundacetone has a neuroprotective effect against oxidative stress[1].
Related Catalog
References

[1]. Tuy An Trinh, et al. Protective Effect of Osmundacetone against Neurological Cell Death Caused by Oxidative Glutamate Toxicity. Biomolecules.2021 Feb 22;11(2):328.

 Chemical & Physical Properties

Density 1.264g/cm3
Boiling Point 382.5ºC at 760mmHg
Melting Point 173-175ºC
Molecular Formula C10H10O3
Molecular Weight 178.18500
Flash Point 199.3ºC
Exact Mass 178.06300
PSA 57.53000
LogP 1.70000
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.637
Storage condition 2-8℃
Water Solubility Methanol

 Synthetic Route

~14%

Osmundacetone Structure

Osmundacetone

CAS#:123694-03-1

Literature: US2003/144316 A1, ;

~54%

Osmundacetone Structure

Osmundacetone

CAS#:123694-03-1

Literature: Synthetic Communications, , vol. 33, # 6 p. 1019 - 1045

~%

Osmundacetone Structure

Osmundacetone

CAS#:123694-03-1

Literature: Bioscience, Biotechnology and Biochemistry, , vol. 74, # 4 p. 741 - 745

 Synonyms

3,4-dihydroxybenzalacetone
4-(3,4-dihydroxyphenyl)-(E)-3-buten-2-one
4-(3,4-Dihydroxyphenyl)-3-buten-2-one
4-(3,4-dihydroxy-phenyl)-but-3-en-2-one
(3E)-4-(3,4-dihydroxyphenyl)-but-3-en-2-one
3-Buten-2-one,4-(3,4-dihydroxyphenyl)-,(3E)
MFCD00916691
4-(3,4-Dihydroxy-phenyl)-but-3-en-2-on
3-Buten-2-one,4-(3,4-dihydroxyphenyl)-,(E)
(E)-3,4-Dihydroxybenzylideneacetone
Osmundacetone
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