PF 05089771

Modify Date: 2024-01-13 17:17:15

PF 05089771 structure	Common Name	PF 05089771
	CAS Number	1235403-62-9	Molecular Weight	500.35400
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₂Cl₂FN₅O₃S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PF 05089771

PF 05089771 is a Nav1.7 channel blocker extracted from patent WO/2010/079443 A1, compound example 788, has an IC50 of 8.6 nM.

Name	4-[2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide
Synonym	More Synonyms

Description	PF 05089771 is a Nav1.7 channel blocker extracted from patent WO/2010/079443 A1, compound example 788, has an IC50 of 8.6 nM.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Others
References	[1]. Norinder U, et al. QSAR investigation of NaV1.7 active compounds using the SVM/Signature approach and the Bioclipse Modeling platform. Bioorg Med Chem Lett. 2013 Jan 1;23(1):261-3. [2]. BEAUDOIN, et al. SULFONAMIDE DERIVATIVES . Patent WO/2010/079443 A1.

Description

PF 05089771 is a Nav1.7 channel blocker extracted from patent WO/2010/079443 A1, compound example 788, has an IC50 of 8.6 nM.

Related Catalog

Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel

Research Areas >> Others

References

[1]. Norinder U, et al. QSAR investigation of NaV1.7 active compounds using the SVM/Signature approach and the Bioclipse Modeling platform. Bioorg Med Chem Lett. 2013 Jan 1;23(1):261-3.

[2]. BEAUDOIN, et al. SULFONAMIDE DERIVATIVES . Patent WO/2010/079443 A1.

Molecular Formula	C₁₈H₁₂Cl₂FN₅O₃S₂
Molecular Weight	500.35400
Exact Mass	498.97400
PSA	159.61000
LogP	6.88940
Storage condition	2-8℃

(1aR,12bS)-8-Cyclohexyl-11-fluoro-N-((1-methylcyclopropyl)sulfonyl)-1a-((3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-1,1a,2,2b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide

PF 05089771

DC Chemicals Limited
China
Product Name: PF 05089771
Price: $500.0/100mg $900.0/250mg $1800.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-(2-(3-amino-1H-pyrazol-4-yl)-4-chlorophenoxy)-5-chloro-2-fluoro-N-(thiazol-4-yl)benzenesulfonamideMolecular Weight: 500.35
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Price: $462/10mM*1mLinDMSO

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PF 05089771

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