microcystin LY

Modify Date: 2024-02-05 14:06:19

microcystin LY Structure
microcystin LY structure
Common Name microcystin LY
CAS Number 123304-10-9 Molecular Weight 1002.16
Density 1.28g/cm3 Boiling Point 1310.2ºC at 760mmHg
Molecular Formula C52H71N7O13 Melting Point N/A
MSDS N/A Flash Point 746.2ºC

 Use of microcystin LY


Microcystin-LY, a cyclic heptapeptide toxin from the cyanobacterium Microcystis aeruginosa[2], acts as an activator of the Nrf2 pathway to induce oxidative stress response, and the induction effect is most obvious at 3μM.[1].

 Names

Name Algae bloom toxin,Biotoxin,Cyanobacterial toxin
Synonym More Synonyms

 microcystin LY Biological Activity

Description Microcystin-LY, a cyclic heptapeptide toxin from the cyanobacterium Microcystis aeruginosa[2], acts as an activator of the Nrf2 pathway to induce oxidative stress response, and the induction effect is most obvious at 3μM.[1].
Related Catalog
Target

Nrf2[1]

References

[1]. Lundqvist J, et al. Microcystins activate nuclear factor erythroid 2-related factor 2 (Nrf2) in human liver cells in vitro - Implications for an oxidative stress induction by microcystins. Toxicon. 2017 Feb;126:47-50.  

[2]. Stoner RD, et al. The effects of single L-amino acid substitutions on the lethal potencies of the microcystins. Toxicon. 1989;27(7):825-8.  

 Chemical & Physical Properties

Density 1.28g/cm3
Boiling Point 1310.2ºC at 760mmHg
Molecular Formula C52H71N7O13
Molecular Weight 1002.16
Flash Point 746.2ºC
Exact Mass 1001.51000
PSA 319.91000
LogP 4.10640
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.597
Storage condition −20°C

 Safety Information

Hazard Codes F,T
Risk Phrases R11
Safety Phrases S16
RIDADR UN 1230 3/PG 2

 Synonyms

MFCD10567358