123304-10-9

123304-10-9 structure

Name: microcystin LY
Chemical Name: Algae bloom toxin,Biotoxin,Cyanobacterial toxin
CAS Number: 123304-10-9
Molecular Formula: C₅₂H₇₁N₇O₁₃
Molecular Weight: 1002.16
Catalog: analytical chemistry Standard Food and cosmetics standards
Create Date: 2018-03-03 08:00:00
Modify Date: 2024-02-05 14:06:19
Microcystin-LY, a cyclic heptapeptide toxin from the cyanobacterium Microcystis aeruginosa[2], acts as an activator of the Nrf2 pathway to induce oxidative stress response, and the induction effect is most obvious at 3μM.[1].

Name	Algae bloom toxin,Biotoxin,Cyanobacterial toxin
Synonyms	MFCD10567358

Description	Microcystin-LY, a cyclic heptapeptide toxin from the cyanobacterium Microcystis aeruginosa[2], acts as an activator of the Nrf2 pathway to induce oxidative stress response, and the induction effect is most obvious at 3μM.[1].
Related Catalog	Signaling Pathways >> NF-κB >> Keap1-Nrf2 Research Areas >> Others
Target	Nrf2[1]
References	[1]. Lundqvist J, et al. Microcystins activate nuclear factor erythroid 2-related factor 2 (Nrf2) in human liver cells in vitro - Implications for an oxidative stress induction by microcystins. Toxicon. 2017 Feb;126:47-50. [2]. Stoner RD, et al. The effects of single L-amino acid substitutions on the lethal potencies of the microcystins. Toxicon. 1989;27(7):825-8.