Microcystin-LA structure
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Common Name | Microcystin-LA | ||
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CAS Number | 96180-79-9 | Molecular Weight | 910.064 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 1237.0±65.0 °C at 760 mmHg | |
Molecular Formula | C46H67N7O12 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 701.9±34.3 °C |
Use of Microcystin-LAMicrocystin LA, a natural toxin, exerts its cytotoxic exects by inhibiting the serine-threonine protein phosphatases PP1 and PP2A with IC50s of 0.3 and 0.3 nM, respectively[1]. |
Name | (5R,8S,11R,12S,15S,18S,19S,22R)-18-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dienyl]-1,5,12,15,19-pentamethyl-2-methylidene-8-(2-methylpropyl)-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptazacyclopentacosane-11,22-dicarboxylic acid |
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Synonym | More Synonyms |
Description | Microcystin LA, a natural toxin, exerts its cytotoxic exects by inhibiting the serine-threonine protein phosphatases PP1 and PP2A with IC50s of 0.3 and 0.3 nM, respectively[1]. |
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Related Catalog | |
In Vitro | Microcystin LA inhibit PP1 and PP2A quite potently and specifically relative to other known phosphatases, such as PP2B (calcineurin), PP2C, and the tyrosine phosphatases[1]. |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 1237.0±65.0 °C at 760 mmHg |
Molecular Formula | C46H67N7O12 |
Molecular Weight | 910.064 |
Flash Point | 701.9±34.3 °C |
Exact Mass | 909.484741 |
PSA | 299.68000 |
LogP | -0.52 |
Vapour Pressure | 0.0±0.3 mmHg at 25°C |
Index of Refraction | 1.574 |
(5R,8S,11R,12S,15S,18S,19S,22R)-18-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dien-1-yl]-1,5,12,15,19-pentamethyl-2-methylidene-8-(2-methylpropyl)-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptaazacyclopentacosane-11,22-dicarboxylic acid |
Toxin BE 4 |
Cyanoginosin-LA |
(5R,8S,11R,12S,15S,18S,19S,22R)-8-Isobutyl-18-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenyl-1,3-heptadien-1-yl]-1,5,12,15,19-pentamethyl-2-methylene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptaazacyclopentacosane-11,22-dicarboxylic acid |
1,4,7,10,14,17,21-Heptaazacyclopentacosane-11,22-dicarboxylic acid, 18-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenyl-1,3-heptadien-1-yl]-1,5,12,15,19-pentamethyl-2-methylene-8-(2-methylpropyl)-3,6,9,13,16,20,25-heptaoxo-, (5R,8S,11R,12S,15S,18S,19S,22R)- |