Pefloxacin-D5

Modify Date: 2024-01-08 18:08:03

Pefloxacin-D5 Structure
Pefloxacin-D5 structure
Common Name Pefloxacin-D5
CAS Number 1228182-51-1 Molecular Weight 338.39
Density N/A Boiling Point N/A
Molecular Formula C17H15D5FN3O3 Melting Point N/A
MSDS USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Pefloxacin-D5


Pefloxacin-d5 is the deuterium labeled 4-Nitrobenzonitrile[1].

 Names

Name 6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1-(1,1,2,2,2-pentadeuterioethyl)quinoline-3-carboxylic acid
Synonym More Synonyms

 Pefloxacin-D5 Biological Activity

Description Pefloxacin-d5 is the deuterium labeled 4-Nitrobenzonitrile[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

 Chemical & Physical Properties

Molecular Formula C17H15D5FN3O3
Molecular Weight 338.39
Exact Mass 338.18000
PSA 65.78000
LogP 1.61340

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases 22-52
RIDADR NONH for all modes of transport

 Synonyms

Pefloxacine-d5
1-Ethyl-d5-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
Pefloxacin-d5