EP3 antagonist 3

Modify Date: 2024-01-23 15:02:16

EP3 antagonist 3 structure	Common Name	EP3 antagonist 3
	CAS Number	1227827-88-4	Molecular Weight	362.38
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₈N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EP3 antagonist 3

EP3 antagonist 3 (compound 2) is an orally active, potent and selective EP3 antagonist, with a pKi of 8.3. EP3 antagonist 3 shows excellent pharmacokinetic properties. EP3 antagonist 3 can be used for overactive bladder (OAB) research[1].

Name	EP3 antagonist 3

Description	EP3 antagonist 3 (compound 2) is an orally active, potent and selective EP3 antagonist, with a pKi of 8.3. EP3 antagonist 3 shows excellent pharmacokinetic properties. EP3 antagonist 3 can be used for overactive bladder (OAB) research[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Neurological Disease
Target	EP3 Receptor:8.3 (pKi)
References	[1]. Jin J, et al. Novel 3-Oxazolidinedione-6-aryl-pyridinones as Potent, Selective, and Orally Active EP3 Receptor Antagonists. ACS Med Chem Lett. 2010 May 14;1(7):316-20.

Molecular Formula	C₂₁H₁₈N₂O₄
Molecular Weight	362.38
InChIKey	HXVAXOYPIPUCRY-UHFFFAOYSA-N
SMILES	CC(C)C1(c2ccc(-c3ccc4ccccc4c3)[nH]c2=O)OC(=O)NC1=O

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EP3 antagonist 3

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