1227827-88-4

1227827-88-4 structure

Name: EP3 antagonist 3
Chemical Name: EP3 antagonist 3
CAS Number: 1227827-88-4
Molecular Formula: C₂₁H₁₈N₂O₄
Molecular Weight: 362.38
Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
Create Date: 2022-09-21 10:17:11
Modify Date: 2024-01-23 15:02:16
EP3 antagonist 3 (compound 2) is an orally active, potent and selective EP3 antagonist, with a pKi of 8.3. EP3 antagonist 3 shows excellent pharmacokinetic properties. EP3 antagonist 3 can be used for overactive bladder (OAB) research[1].

Name	EP3 antagonist 3

Description	EP3 antagonist 3 (compound 2) is an orally active, potent and selective EP3 antagonist, with a pKi of 8.3. EP3 antagonist 3 shows excellent pharmacokinetic properties. EP3 antagonist 3 can be used for overactive bladder (OAB) research[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Neurological Disease
Target	EP3 Receptor:8.3 (pKi)
References	[1]. Jin J, et al. Novel 3-Oxazolidinedione-6-aryl-pyridinones as Potent, Selective, and Orally Active EP3 Receptor Antagonists. ACS Med Chem Lett. 2010 May 14;1(7):316-20.

Molecular Formula	C₂₁H₁₈N₂O₄
Molecular Weight	362.38