(Rac)-Tezacaftor

Modify Date: 2025-08-25 22:57:37

(Rac)-Tezacaftor Structure
(Rac)-Tezacaftor structure
Common Name (Rac)-Tezacaftor
CAS Number 1226709-85-8 Molecular Weight 520.50
Density N/A Boiling Point N/A
Molecular Formula C26H27F3N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (Rac)-Tezacaftor


(Rac)-Tezacaftor ((Rac)-VX-661) is a racemate of Tezacaftor (HY-15448). Tezacaftor is a F508del CFTR corrector. (Rac)-Tezacaftor can be used for the research of cystic fibrosis[1].

 Names

Name (Rac)-Tezacaftor

 (Rac)-Tezacaftor Biological Activity

Description (Rac)-Tezacaftor ((Rac)-VX-661) is a racemate of Tezacaftor (HY-15448). Tezacaftor is a F508del CFTR corrector. (Rac)-Tezacaftor can be used for the research of cystic fibrosis[1].
Related Catalog
References

[1]. Keating D, et al. VX-445-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles. N Engl J Med. 2018 Oct 25;379(17):1612-1620.  

 Chemical & Physical Properties

Molecular Formula C26H27F3N2O6
Molecular Weight 520.50
InChIKey MJUVRTYWUMPBTR-UHFFFAOYSA-N
SMILES CC(C)(CO)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c(F)cc2n1CC(O)CO
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