(Rac)-Tezacaftor

Names

[ CAS No. ]:
1226709-85-8

[ Name ]:
(Rac)-Tezacaftor

Biological Activity

[Description]:

(Rac)-Tezacaftor ((Rac)-VX-661) is a racemate of Tezacaftor (HY-15448). Tezacaftor is a F508del CFTR corrector. (Rac)-Tezacaftor can be used for the research of cystic fibrosis[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> CFTR
Research Areas >> Inflammation/Immunology

[References]

[1]. Keating D, et al. VX-445-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles. N Engl J Med. 2018 Oct 25;379(17):1612-1620.  

Chemical & Physical Properties

[ Molecular Formula ]:
C26H27F3N2O6

[ Molecular Weight ]:
520.50

Related Compounds

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