Protriptyline hydrochloride
Modify Date: 2025-08-26 17:54:45
Protriptyline hydrochloride structure
|
Common Name | Protriptyline hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 1225-55-4 | Molecular Weight | 299.838 | |
| Density | N/A | Boiling Point | 407.7ºC at 760 mmHg | |
| Molecular Formula | C19H22ClN | Melting Point | 169-171° | |
| MSDS | Chinese USA | Flash Point | 198.3ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of Protriptyline hydrochlorideProtriptyline is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Unique among the TCAs, protriptyline tends to be energizing instead of sedating, used for narcolepsy to achieve a wakefulness-promoting effect. |
| Name | protriptyline hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | Protriptyline is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Unique among the TCAs, protriptyline tends to be energizing instead of sedating, used for narcolepsy to achieve a wakefulness-promoting effect. |
|---|---|
| Related Catalog |
| Boiling Point | 407.7ºC at 760 mmHg |
|---|---|
| Melting Point | 169-171° |
| Molecular Formula | C19H22ClN |
| Molecular Weight | 299.838 |
| Flash Point | 198.3ºC |
| Exact Mass | 299.144073 |
| PSA | 12.03000 |
| LogP | 5.49480 |
| Vapour Pressure | 7.41E-07mmHg at 25°C |
| Storage condition | 2-8°C |
| Water Solubility | H2O: soluble50mg/mL |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H312-H315-H319-H332-H335 |
| Precautionary Statements | P261-P280-P301 + P310-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | 20/21/22-36/37/38 |
| Safety Phrases | 26-36-45-36/37-16-7 |
| RIDADR | UN 3249 |
| RTECS | HP1400000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
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Proc. Soc. Exp. Biol. Med. 216(3) , 424-8, (1997) Forty-nine "standard" compounds known to be useful in the treatment of other diseases were tested for their suppressive activity against the trypomastigotes of Trypanosoma cruzi-infected mice. The mos... |
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Protriptyline, chronic tension-type headaches, and weight loss in women.
Headache 37(7) , 433-6, (1997) Twenty-five women with chronic tension-type headaches were treated with protriptyline for 3 months, with attention paid to days of monthly headaches before and while taking the medication, as well as ... |
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Respiration 64 Suppl 1 , 35-8, (1997) Patients with neuromuscular disease may suffer from nocturnal respiratory failure despite normal daytime respiratory function. The physiological reduction in muscle tone during sleep may be life-threa... |
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