1435934-21-6

1435934-21-6 structure
1435934-21-6 structure
  • Name: Protriptyline (N-methyl-d3) (hydrochloride)
  • Chemical Name: Protriptyline (N-methyl-d3) (hydrochloride)
  • CAS Number: 1435934-21-6
  • Molecular Formula: C19H19D3ClN
  • Molecular Weight: 266.40
  • Catalog: Signaling Pathways Neuronal Signaling AChE
  • Create Date: 2021-10-07 17:45:15
  • Modify Date: 2024-04-04 20:05:55
  • Protriptyline (N-Methyl-d3) hydrochloride is the deuterium labeled Protriptyline hydrochloride. Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Unique among the TCAs, protriptyline tends to be energizing instead of sedating, used for narcolepsy to achieve a wakefulness-promoting effect[1].

Name Protriptyline (N-methyl-d3) (hydrochloride)
Description Protriptyline (N-Methyl-d3) hydrochloride is the deuterium labeled Protriptyline hydrochloride. Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Unique among the TCAs, protriptyline tends to be energizing instead of sedating, used for narcolepsy to achieve a wakefulness-promoting effect[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Hudgel DW. Pharmacologic treatment of obstructive sleep apnea. J Lab Clin Med. 1995;126(1):13-18.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Molecular Formula C19H19D3ClN
Molecular Weight 266.40