TC-I 2014

Modify Date: 2025-08-25 11:12:29

TC-I 2014 structure	Common Name	TC-I 2014
	CAS Number	1221349-53-6	Molecular Weight	467.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₁₉F₆N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TC-I 2014

TC-I 2014 (compound 5) is a potent Benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonist, with IC50 values of 0.8 nM, 3.0 nM and 4.4 nM for canine, human and rat channels respectively. TC-I 2014 exhibits antiallodynic properties in pain models[1].

Name	TC-I 2014

Description	TC-I 2014 (compound 5) is a potent Benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonist, with IC50 values of 0.8 nM, 3.0 nM and 4.4 nM for canine, human and rat channels respectively. TC-I 2014 exhibits antiallodynic properties in pain models[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Neurological Disease
Target	TRPM8[1].
References	[1]. Parks DJ, et Design and optimization of benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonists. J Med Chem. 2011 Jan 13;54(1):233-47.

Molecular Formula	C₂₃H₁₉F₆N₃O
Molecular Weight	467.41

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TC-I 2014
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Purity: 98.0%
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.