949467-71-4

949467-71-4 structure

Name: TC-T 6000
Chemical Name: TC-T 6000
CAS Number: 949467-71-4
Molecular Formula: C₂₆H₄₈N₈O₂
Molecular Weight: 504.71
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Monoamine Transporter
Create Date: 2022-03-28 04:42:22
Modify Date: 2025-08-25 16:28:47
hENT4-IN-1 is a potent and selective human ENT4 (equilibrative nucleoside transporter 4) inhibitor with an IC50 of 74.4 nM[1].

Name	TC-T 6000
Synonyms	2,2'-({4,8-bis[bis(2-methylpropyl)amino]pyrimido[5,4-d]pyrimidine-2,6-diyl}diimino)diethanol Ethanol, 2,2'-[[4,8-bis[bis(2-methylpropyl)amino]pyrimido[5,4-d]pyrimidine-2,6-diyl]diimino]bis- 2,2'-{[4,8-Bis(diisobutylamino)pyrimido[5,4-d]pyrimidine-2,6-diyl]diimino}diethanol 2,2'-[[4,8-Bis[bis(2-methylpropyl)amino]pyrimido[5,4-d]pyrimidine-2,6-diyl]diimino]bis-ethanol

Description	hENT4-IN-1 is a potent and selective human ENT4 (equilibrative nucleoside transporter 4) inhibitor with an IC50 of 74.4 nM[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Monoamine Transporter
References	[1]. Wang C, et al. Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4). Biochem Pharmacol. 2013 Dec 1;86(11):1531-40.