CCR1 inhibitor 19e
Modify Date: 2025-08-25 09:50:39
CCR1 inhibitor 19e structure
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Common Name | CCR1 inhibitor 19e | ||
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| CAS Number | 1220026-26-5 | Molecular Weight | 425.438 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H16FN5O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CCR1 inhibitor 19eCCR1 inhibitor 19e is a novel potent, selective CCR1 antagonist with IC50 of 6.8 nM, inhibits CCR1chemotaxis in THP-1 cells with IC50 of 28 nM. |
| Name | CCR1 inhibitor 19e |
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| Description | CCR1 inhibitor 19e is a novel potent, selective CCR1 antagonist with IC50 of 6.8 nM, inhibits CCR1chemotaxis in THP-1 cells with IC50 of 28 nM. |
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| References | References 1. Harcken C, et al. Bioorg Med Chem Lett. 2018 Dec 13. pii: S0960-894X(18)30958-2. doi: 10.1016/j.bmcl.2018.12.024. View Related Products by Target Chemokine Receptor (CCR and CXCR) |
| Molecular Formula | C20H16FN5O3S |
|---|---|
| Molecular Weight | 425.438 |
| InChIKey | DCHROQCNJDJPGN-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)c1cc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1 |