CCR1 inhibitor 19e

Names

[ CAS No. ]:
1220026-26-5

[ Name ]:
CCR1 inhibitor 19e

Biological Activity

[Description]:

CCR1 inhibitor 19e is a novel potent, selective CCR1 antagonist with IC50 of 6.8 nM, inhibits CCR1chemotaxis in THP-1 cells with IC50 of 28 nM.

[References]

References 1. Harcken C, et al. Bioorg Med Chem Lett. 2018 Dec 13. pii: S0960-894X(18)30958-2. doi: 10.1016/j.bmcl.2018.12.024. View Related Products by Target Chemokine Receptor (CCR and CXCR)

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₆FN₅O₃S

[ Molecular Weight ]:
425.438

Related Compounds

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