Purine, 2-amino-6- (methylthio)-

Modify Date: 2024-01-10 19:32:55

Purine, 2-amino-6- (methylthio)- Structure
Purine, 2-amino-6- (methylthio)- structure
Common Name Purine, 2-amino-6- (methylthio)-
CAS Number 1198-47-6 Molecular Weight 181.218
Density 1.6±0.1 g/cm3 Boiling Point 622.1±58.0 °C at 760 mmHg
Molecular Formula C6H7N5S Melting Point 234-237ºC
MSDS Chinese USA Flash Point 330.0±32.3 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Names

Name 6-methylsulfanyl-7H-purin-2-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 622.1±58.0 °C at 760 mmHg
Melting Point 234-237ºC
Molecular Formula C6H7N5S
Molecular Weight 181.218
Flash Point 330.0±32.3 °C
Exact Mass 181.042221
PSA 105.78000
LogP 0.82
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.761
Storage condition -20°C

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H315-H318-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases 24/25-39-26
RIDADR NONH for all modes of transport
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles16

More Articles
Liquid Chromatography with Amperometric Detection at a Silver Based Detector for the Determination of Thiocompounds: Application to the Assay of Thiopurine Antimetabolites in Urine.

Anal. Chem. 87 , 6730-5, (2015)

A silver amperometric detector coupled to liquid chromatography (LC) was used for the determination of 6-thioguanine (6-TG) and two of its metabolites, thiouric acid (TU) and 2-amino-6-mercaptopurine ...

The syntheses and properties of tricyclic pyrrolo[2,3-d]pyrimidine analogues of S6-methylthioguanine and O6-methylguanine.

Org. Biomol. Chem. 4(9) , 1723-9, (2006)

The syntheses of novel tricyclic pyrrolo[2,3-d]pyrimidine analogues of S6-methylthioguanine are described. The crystal structures and pKa values of these and related O6-methylguanine analogues are rep...

Reference intervals for thiopurine S-methyltransferase activity in red blood cells using 6-thioguanine as substrate and rapid non-extraction liquid chromatography.

Ann. Clin. Biochem. 41(Pt 4) , 303-8, (2004)

Although widely used, thiopurine drugs have a narrow therapeutic index and treatment can result in life-threatening toxicity, the basis being pharmacogenetic variation in thiopurine metabolism by thio...

 Synonyms

2-Amino-6-methylthiopurine
6-Methylthioguanine
6-(Methylsulfanyl)-7H-purin-2-amine
Purine, 2-amino-6- (methylthio)-
S-methylthioguanine
6-(Methylsulfanyl)-1H-purin-2-amine
2-Amino-6-methylmercaptopurine
EINECS 214-833-4
1H-Purin-2-amine, 6- (methylthio)-
6-(methylsulfanyl)-7H-purin-2-ylamine
7H-Purin-2-amine, 6-(methylthio)-
MFCD00044701
1H-purin-2-amine, 6-(methylthio)-
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