Galanin (human) acetate salt

Modify Date: 2024-01-02 17:11:32

Galanin (human) acetate salt structure	Common Name	Galanin (human) acetate salt
	CAS Number	119418-04-1	Molecular Weight	3157.41000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃₉H₂₁₀N₄₂O₄₃	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of Galanin (human) acetate salt

Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM.

Name	Galanin human
Synonym	More Synonyms

Description	Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor Peptides Research Areas >> Neurological Disease
Target	Kd: 1 nM (GalR1 receptor), 1 nM (GalR2 receptor)[2]
In Vitro	Galanin (1-30), human (Gal1-30) is an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM[1]. Galanin (1-30), human displaces 125I-labeled rat galanin with a Kd of 0.5 nM. Galanin (1-30), human (hGal) causes contractions of isolated longitudinal rat fundus strips, with an ED50 of 13.8 ± 1.6 nM[2].
References	[1]. Hua XY, et al. Galanin acts at GalR1 receptors in spinal antinociception: synergy with morphine and AP-5. J Pharmacol Exp Ther. 2004 Feb;308(2):574-82. [2]. Schmidt WE, et al. Isolation and primary structure of pituitary human galanin, a 30-residue nonamidated neuropeptide. Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11435-9.

Molecular Formula	C₁₃₉H₂₁₀N₄₂O₄₃
Molecular Weight	3157.41000
Exact Mass	3155.55000
PSA	1367.68000

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This study aimed to investigate the association of galanin (GAL) gene and the development of depression in the Chinese Han population.A total of 700 patients with depression who met the diagnostic cri...

MFCD00135986

Galanin,Human

Galanin-1-30

Galanin (1-30), human