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36204-23-6

36204-23-6 structure
36204-23-6 structure
  • Name: Fibrinopeptide B (human) acetate salt
  • Chemical Name: Fibrinopeptide B
  • CAS Number: 36204-23-6
  • Molecular Formula: C66H93N19O25
  • Molecular Weight: 1552.56000
  • Catalog: Biochemical Peptide
  • Create Date: 2018-08-14 21:37:12
  • Modify Date: 2024-01-01 22:22:24
  • Fibrinopeptide B, human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin.

Name Fibrinopeptide B
Synonyms pyroGlu-Gly-Val-Asn-Asp-Asn-Glu-Glu-Gly-Phe-Phe-Ser-Ala-Arg
Pyr-GVNDNEEGFFSAR
Fibrinopeptide B, human
Description Fibrinopeptide B, human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin.
Related Catalog
In Vitro Fibrinopeptide B, human is released from the amino-terminus of the B 3-chains of fibrinogen by thrombin. Fibrinopeptide B, human (hFpB, 10 nM) causes directed cell migration of neutrophils (PMN), and fibroblasts. Fibrinopeptide B, human also possesses potent chemotactic activity relative to human complement (C5a), leukotriene B4 (LTB4), and formyl-methionylleucyl-phenylalanine (fMLP), and for fibroblasts its chemotactic activity is comparable to that of platelet-derived growth factor. However, Fibrinopeptide B, human is not chemotactic for monocytes, and shows no interaction with PMN receptor for C5a, LTB4, or fMLP[1].
References

[1]. Senior RM, et al. Effects of fibrinogen derivatives upon the inflammatory response. Studies with human fibrinopeptide B. J Clin Invest. 1986 Mar;77(3):1014-9.

Molecular Formula C66H93N19O25
Molecular Weight 1552.56000
Exact Mass 1551.66000
PSA 724.91000
Storage condition −20°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3