2-chloro-3'-deoxyadenosine

Modify Date: 2025-09-21 21:56:07

2-chloro-3'-deoxyadenosine structure	Common Name	2-chloro-3'-deoxyadenosine
	CAS Number	115044-75-2	Molecular Weight	285.69
	Density	2.03g/cm3	Boiling Point	547.6ºC at 760mmHg
	Molecular Formula	C₁₀H₁₂ClN₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	285ºC

Use of 2-chloro-3'-deoxyadenosine

2-Chloro-3′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	(2R,3R,5S)-2-(6-amino-2-chloropurin-9-yl)-5-(hydroxymethyl)oxolan-3-ol
Synonym	More Synonyms

Description	2-Chloro-3′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	2.03g/cm3
Boiling Point	547.6ºC at 760mmHg
Molecular Formula	C₁₀H₁₂ClN₅O₃
Molecular Weight	285.69
Flash Point	285ºC
Exact Mass	285.06300
PSA	119.31000
LogP	0.28380
Vapour Pressure	7.95E-13mmHg at 25°C
Index of Refraction	1.87
InChIKey	HNSLUZJFGNTTEV-OBXARNEKSA-N
SMILES	Nc1nc(Cl)nc2c1ncn2C1OC(CO)CC1O

((2S,4R,5R)-4-a...

CAS#:1504571-49-6

~36%

2-chloro-3'-deo...

CAS#:115044-75-2

Literature: Vodnala, Suman K.; Lundbaeck, Thomas; Yeheskieli, Esther; Sjoeberg, Birger; Gustavsson, Anna-Lena; Svensson, Richard; Olivera, Gabriela C.; Eze, Anthonius A.; De Koning, Harry P.; Hammarstroem, Lars G. J.; Rottenberg, Martin E. Journal of Medicinal Chemistry, 2013 , vol. 56, # 24 p. 9861 - 9873

2-Chloroadenosine

CAS#:146-77-0

2-chloro-3'-deo...

CAS#:115044-75-2

Literature: Rosowsky, Andre; Solan, Vishnu C.; Sodroski, Joseph G.; Ruprecht, Ruth M. Journal of Medicinal Chemistry, 1989 , vol. 32, # 5 p. 1135 - 1140

N/A

CAS#:119530-57-3

2-chloro-3'-deo...

CAS#:115044-75-2

Literature: Rosowsky, Andre; Solan, Vishnu C.; Sodroski, Joseph G.; Ruprecht, Ruth M. Journal of Medicinal Chemistry, 1989 , vol. 32, # 5 p. 1135 - 1140

2-chloroadenine

CAS#:1839-18-5

β-D-erythro-Pen...

CAS#:90580-88-4

2-chloro-3'-deo...

CAS#:115044-75-2

N/A

CAS#:119530-58-4

2-chloroadenine

CAS#:1839-18-5

2-chloro-3'-deo...

CAS#:115044-75-2

N/A

CAS#:119530-61-9

Literature: Rosowsky, Andre; Solan, Vishnu C.; Sodroski, Joseph G.; Ruprecht, Ruth M. Journal of Medicinal Chemistry, 1989 , vol. 32, # 5 p. 1135 - 1140

biodribin

C10H14ClN5O3

Adenosine,2-chloro-3'-deoxy

2-Chloro-3'-deoxyadenosine

2-chlorocordycepin

3'-Deoxy-2-chloroadenosine

UNII-JYW18Y92UP

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2-chloro-3'-deoxyadenosine

Use of 2-chloro-3'-deoxyadenosine

Names

2-chloro-3'-deoxyadenosine Biological Activity

Chemical & Physical Properties

Synthetic Route

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.