115044-75-2

115044-75-2 structure

Name: 2-chloro-3'-deoxyadenosine
Chemical Name: (2R,3R,5S)-2-(6-amino-2-chloropurin-9-yl)-5-(hydroxymethyl)oxolan-3-ol
CAS Number: 115044-75-2
Molecular Formula: C₁₀H₁₂ClN₅O₃
Molecular Weight: 285.69
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-10-18 12:19:49
Modify Date: 2024-01-09 16:37:43
2-Chloro-3′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	(2R,3R,5S)-2-(6-amino-2-chloropurin-9-yl)-5-(hydroxymethyl)oxolan-3-ol
Synonyms	biodribin C10H14ClN5O3 Adenosine,2-chloro-3'-deoxy 2-Chloro-3'-deoxyadenosine 2-chlorocordycepin 3'-Deoxy-2-chloroadenosine UNII-JYW18Y92UP

Description	2-Chloro-3′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.