(Z)-FeCP-oxindole structure
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Common Name | (Z)-FeCP-oxindole | ||
|---|---|---|---|---|
| CAS Number | 1137967-28-2 | Molecular Weight | 329.173 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H15FeNO | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (Z)-FeCP-oxindole(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM[1]. |
| Name | (Z)-FeCP-oxindole |
|---|---|
| Synonym | More Synonyms |
| Description | (Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C19H15FeNO |
|---|---|
| Molecular Weight | 329.173 |
| Exact Mass | 329.050293 |
| InChIKey | MTGBTDOTYGXLBK-UHFFFAOYSA-M |
| SMILES | [Fe+2].[O-]c1[nH]c2ccccc2c1C=C1C=CC=C1.c1cc[cH-]c1 |
| Iron(2+) 2,4-cyclopentadienide 2-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-cyclopentadienide (1:1:1) |