Z-DEVD-AFC

Modify Date: 2024-01-06 20:10:40

Z-DEVD-AFC Structure
Z-DEVD-AFC structure
Common Name Z-DEVD-AFC
CAS Number 1135416-11-3 Molecular Weight 821.707
Density 1.5±0.1 g/cm3 Boiling Point 1160.9±65.0 °C at 760 mmHg
Molecular Formula C36H38F3N5O14 Melting Point N/A
MSDS N/A Flash Point 655.9±34.3 °C

 Use of Z-DEVD-AFC


Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity[1].

 Names

Name Z-DEVD-AFC
Synonym More Synonyms

 Z-DEVD-AFC Biological Activity

Description Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity[1].
Related Catalog
References

[1]. Santiago AR, et al. High glucose induces caspase-independent cell death in retinal neural cells. Neurobiol Dis. 2007;25(3):464-472.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 1160.9±65.0 °C at 760 mmHg
Molecular Formula C36H38F3N5O14
Molecular Weight 821.707
Flash Point 655.9±34.3 °C
Exact Mass 821.236755
LogP 4.15
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.591

 Synonyms

N-[(Benzyloxy)carbonyl]-L-α-aspartyl-L-α-glutamyl-L-valyl-N-[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl]-L-α-asparagine
L-α-Asparagine, N-[(phenylmethoxy)carbonyl]-L-α-aspartyl-L-α-glutamyl-L-valyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-
Z-DEVD-AFC