219138-08-6

219138-08-6 structure

Name: Z-Val-Asp-Val-Ala-Asp-AFC
Chemical Name: z-vdvad-afc
CAS Number: 219138-08-6
Molecular Formula: C₃₉H₄₅F₃N₆O₁₃
Molecular Weight: 862.80
Catalog: Biochemical Amino acids and their derivatives Aspartic acid derivative
Create Date: 2018-12-25 16:42:23
Modify Date: 2025-08-26 19:50:04
Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1].

Name	z-vdvad-afc
Synonyms	Z-Val-Asp-Ala-Asp-AFC PASE-2 SUBSTRATE I,FLUOROGENIC Z-VAL-ASP-VAL-ALA-ASP-AFC

Description	Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1].
Related Catalog	Research Areas >> Others
References	[1]. Pallepati P, et, al. Mild thermotolerance induced at 40°C protects HeLa cells against activation of death receptor-mediated apoptosis by hydrogen peroxide. Free Radic Biol Med. 2011 Mar 15;50(6):667-79.