Z-Val-Asp-Val-Ala-Asp-AFC

Modify Date: 2024-04-05 14:20:43

Z-Val-Asp-Val-Ala-Asp-AFC Structure
Z-Val-Asp-Val-Ala-Asp-AFC structure
Common Name Z-Val-Asp-Val-Ala-Asp-AFC
CAS Number 219138-08-6 Molecular Weight 862.80
Density N/A Boiling Point N/A
Molecular Formula C39H45F3N6O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Z-Val-Asp-Val-Ala-Asp-AFC


Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1].

 Names

Name z-vdvad-afc
Synonym More Synonyms

 Z-Val-Asp-Val-Ala-Asp-AFC Biological Activity

Description Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1].
Related Catalog
References

[1]. Pallepati P, et, al. Mild thermotolerance induced at 40°C protects HeLa cells against activation of death receptor-mediated apoptosis by hydrogen peroxide. Free Radic Biol Med. 2011 Mar 15;50(6):667-79.  

 Chemical & Physical Properties

Molecular Formula C39H45F3N6O13
Molecular Weight 862.80
Exact Mass 862.30000
PSA 288.64000
LogP 4.29330
Storage condition -15°C

 Synonyms

Z-Val-Asp-Ala-Asp-AFC
PASE-2 SUBSTRATE I,FLUOROGENIC
Z-VAL-ASP-VAL-ALA-ASP-AFC
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