Bromo-PEG1-CH2COOH
Modify Date: 2024-01-14 11:23:40
Bromo-PEG1-CH2COOH structure
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Common Name | Bromo-PEG1-CH2COOH | ||
|---|---|---|---|---|
| CAS Number | 1135131-50-8 | Molecular Weight | 183.001 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 316.4±17.0 °C at 760 mmHg | |
| Molecular Formula | C4H7BrO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 145.2±20.9 °C | |
Use of Bromo-PEG1-CH2COOHBromo-PEG1-CH2COOH is a PROTAC linker can be used in the synthesis of PROTACs[1]. |
| Name | (2-Bromoethoxy)acetic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Bromo-PEG1-CH2COOH is a PROTAC linker can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
[1]. Christopher Michael Semko, et al. C26-linked rapamycin analogs as mtor inhibitors. WO2019212991A1. |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 316.4±17.0 °C at 760 mmHg |
| Molecular Formula | C4H7BrO3 |
| Molecular Weight | 183.001 |
| Flash Point | 145.2±20.9 °C |
| Exact Mass | 181.957855 |
| LogP | 0.22 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.493 |
| Hazard Codes | C |
|---|
| MFCD20637665 |
| Acetic acid, 2-(2-bromoethoxy)- |
| (2-Bromoethoxy)acetic acid |