PEG4-bis(phosphonic acid diethyl ester)

Modify Date: 2024-01-05 18:03:30

PEG4-bis(phosphonic acid diethyl ester) Structure
PEG4-bis(phosphonic acid diethyl ester) structure
Common Name PEG4-bis(phosphonic acid diethyl ester)
CAS Number 106338-06-1 Molecular Weight 466.4
Density N/A Boiling Point N/A
Molecular Formula C16H36O11P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PEG4-bis(phosphonic acid diethyl ester)


PEG4-bis(phosphonic acid diethyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name PEG5-Bis(phosphonic acid diethyl ester)

 PEG4-bis(phosphonic acid diethyl ester) Biological Activity

Description PEG4-bis(phosphonic acid diethyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H36O11P2
Molecular Weight 466.4