nor-Binaltorphimine(nor-BNI)
nor-Binaltorphimine(nor-BNI) structure
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Common Name | nor-Binaltorphimine(nor-BNI) | ||
|---|---|---|---|---|
| CAS Number | 105618-26-6 | Molecular Weight | 734.70800 | |
| Density | 1.63 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C40H45Cl2N3O6 | Melting Point | 280ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of nor-Binaltorphimine(nor-BNI)nor-Binaltorphimine dihydrochloride is a long-acting potent and highly selective kappa opioid receptor antagonist. |
| Name | nor-Binaltorphimine dihydrochloride,17,17'-(Dicyclopropylmethyl)-6,6',7,7'-6,6'-imino-7,7'-binorphinan-3,4',14,14'-tetroldihydrochloride |
|---|---|
| Synonym | More Synonyms |
| Density | 1.63 g/cm3 |
|---|---|
| Melting Point | 280ºC |
| Molecular Formula | C40H45Cl2N3O6 |
| Molecular Weight | 734.70800 |
| Exact Mass | 733.26900 |
| PSA | 121.65000 |
| LogP | 5.30390 |
| Index of Refraction | 1.834 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| RTECS | IO1320000 |
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~%
nor-Binaltorphi... CAS#:105618-26-6 |
| Literature: Journal of Medicinal Chemistry, , vol. 48, # 5 p. 1676 - 1679 |
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~%
nor-Binaltorphi... CAS#:105618-26-6 |
| Literature: Journal of Medicinal Chemistry, , vol. 31, # 4 p. 836 - 841 |
| Precursor 2 | |
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| DownStream 0 | |
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GPR54-dependent stimulation of luteinizing hormone secretion by neurokinin B in prepubertal rats.
PLoS ONE 7(9) , e44344, (2012) Kisspeptin, neurokinin B (NKB) and dynorphin A (Dyn) are coexpressed within KNDy neurons that project from the hypothalamic arcuate nucleus (ARC) to GnRH neurons and numerous other hypothalamic target... |
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Effect of food restriction on cocaine locomotor sensitization in Sprague-Dawley rats: role of kappa opioid receptors.
Psychopharmacology 226(3) , 571-8, (2013) The interaction between repeated cocaine exposure and food restriction on sensitization to the stimulatory effects of cocaine has not been characterized.To compare cocaine sensitization in rats free f... |
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Kappa opioid regulation of anxiety-like behavior during acute ethanol withdrawal
Pharmacol. Biochem. Behav. 102(1) , 44-7, (2012) Withdrawal is one of the defining characteristics of alcohol dependence, and is often characterized by impaired physiological function and enhanced negative affect. Recent evidence suggests that the d... |
| norbinaltorphimine |
| Nor-binaltorphimine2HCl |
| NOR-BNL 2HCL |
| NORBNI |
| NOR-BINALTORPHIMINE DIHYDROCHLORIDE |
| nor-binaltrophimine |
| NOR-BNI DIHYDROCHLORIDE |
| MFCD00069374 |
| N-DeMethylbinaltrorphiMine |
| N-DESMETHYLBINALTORPHIMINE |