nor-Binaltorphimine(nor-BNI)

[ Density]:
1.63 g/cm3

[ Melting Point ]:
280ºC

[ Molecular Formula ]:
C₄₀H₄₅Cl₂N₃O₆

[ Molecular Weight ]:
734.70800

[ Exact Mass ]:
733.26900

[ PSA ]:
121.65000

[ LogP ]:
5.30390

[ Index of Refraction ]:
1.834

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
IO1320000

Click to get detail synthetic route

Precursor

DownStream

GPR54-dependent stimulation of luteinizing hormone secretion by neurokinin B in prepubertal rats.

PLoS ONE 7(9) , e44344, (2012)

Kisspeptin, neurokinin B (NKB) and dynorphin A (Dyn) are coexpressed within KNDy neurons that project from the hypothalamic arcuate nucleus (ARC) to GnRH neurons and numerous other hypothalamic target...

Effect of food restriction on cocaine locomotor sensitization in Sprague-Dawley rats: role of kappa opioid receptors.

Psychopharmacology 226(3) , 571-8, (2013)

The interaction between repeated cocaine exposure and food restriction on sensitization to the stimulatory effects of cocaine has not been characterized.To compare cocaine sensitization in rats free f...

Kappa opioid regulation of anxiety-like behavior during acute ethanol withdrawal

Pharmacol. Biochem. Behav. 102(1) , 44-7, (2012)

Withdrawal is one of the defining characteristics of alcohol dependence, and is often characterized by impaired physiological function and enhanced negative affect. Recent evidence suggests that the d...

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