RS 8359

Modify Date: 2024-02-05 13:52:36

RS 8359 Structure
RS 8359 structure
Common Name RS 8359
CAS Number 105365-76-2 Molecular Weight 252.271
Density 1.4±0.1 g/cm3 Boiling Point 483.6±45.0 °C at 760 mmHg
Molecular Formula C14H12N4O Melting Point N/A
MSDS N/A Flash Point 246.3±28.7 °C

 Use of RS 8359


RS 8359 is a selective and reversible MAO-A inhibitor, with antidepressant activity.

 Names

Name 4-[(7-Hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]be nzonitrile
Synonym More Synonyms

 RS 8359 Biological Activity

Description RS 8359 is a selective and reversible MAO-A inhibitor, with antidepressant activity.
Related Catalog
In Vivo RS 8359 shows relatively little effect upon blood pressure when administered together with tyramine. RS-8359 shows little affinity for the common central nervous system receptors and little anticholinergic effect[1].
References

[1]. Iwata N, et al. Pharmacology of the new reversible inhibitor of monoamine oxidase A, RS-8359. Int Clin Psychopharmacol. 1997 Sep;12 Suppl 5:S3-10.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 483.6±45.0 °C at 760 mmHg
Molecular Formula C14H12N4O
Molecular Weight 252.271
Flash Point 246.3±28.7 °C
Exact Mass 252.101105
PSA 81.83000
LogP 1.12
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.682
Storage condition 2-8℃

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Benzonitrile, 4-[(6,7-dihydro-7-hydroxy-5H-cyclopenta[d]pyrimidin-4-yl)amino]-
4-[(7-Hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]benzonitrile
UNII:79U9T1HIX9
RS 8359