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105365-76-2

105365-76-2 structure
105365-76-2 structure
  • Name: RS 8359
  • Chemical Name: 4-[(7-Hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]be nzonitrile
  • CAS Number: 105365-76-2
  • Molecular Formula: C14H12N4O
  • Molecular Weight: 252.271
  • Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
  • Create Date: 2018-08-02 02:18:52
  • Modify Date: 2024-02-05 13:52:36
  • RS 8359 is a selective and reversible MAO-A inhibitor, with antidepressant activity.

Name 4-[(7-Hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]be nzonitrile
Synonyms Benzonitrile, 4-[(6,7-dihydro-7-hydroxy-5H-cyclopenta[d]pyrimidin-4-yl)amino]-
4-[(7-Hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]benzonitrile
UNII:79U9T1HIX9
RS 8359
Description RS 8359 is a selective and reversible MAO-A inhibitor, with antidepressant activity.
Related Catalog
In Vivo RS 8359 shows relatively little effect upon blood pressure when administered together with tyramine. RS-8359 shows little affinity for the common central nervous system receptors and little anticholinergic effect[1].
References

[1]. Iwata N, et al. Pharmacology of the new reversible inhibitor of monoamine oxidase A, RS-8359. Int Clin Psychopharmacol. 1997 Sep;12 Suppl 5:S3-10.

Density 1.4±0.1 g/cm3
Boiling Point 483.6±45.0 °C at 760 mmHg
Molecular Formula C14H12N4O
Molecular Weight 252.271
Flash Point 246.3±28.7 °C
Exact Mass 252.101105
PSA 81.83000
LogP 1.12
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.682
Storage condition 2-8℃
HS Code 2933990090
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%