Sepimostat
Modify Date: 2025-08-25 16:59:24
Sepimostat structure
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Common Name | Sepimostat | ||
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| CAS Number | 103926-64-3 | Molecular Weight | 373.40800 | |
| Density | 1.39g/cm3 | Boiling Point | 607.4ºC at 760mmHg | |
| Molecular Formula | C21H19N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 321.2ºC | |
Use of SepimostatSepimostat exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat inhibits the Ifenprodil binding with a Ki value of 27.7 µM[1]. |
| Name | (6-carbamimidoylnaphthalen-2-yl) 4-(4,5-dihydro-1H-imidazol-2-ylamino)benzoate |
|---|---|
| Synonym | More Synonyms |
| Description | Sepimostat exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat inhibits the Ifenprodil binding with a Ki value of 27.7 µM[1]. |
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| Related Catalog | |
| In Vivo | Sepimostat (1 to 100 nmol/eye, intravitreal injection) exhibits significant neuroprotective effect[1]. Animal Model: Male Sprague Dawley rats weighing 150-300 g[1]. Dosage: Intravitreal injection. Administration: 1 to 100 nmol/eye. Result: Exhibited neuroprotective effects significantly. |
| References |
| Density | 1.39g/cm3 |
|---|---|
| Boiling Point | 607.4ºC at 760mmHg |
| Molecular Formula | C21H19N5O2 |
| Molecular Weight | 373.40800 |
| Flash Point | 321.2ºC |
| Exact Mass | 373.15400 |
| PSA | 112.59000 |
| LogP | 3.35160 |
| Vapour Pressure | 1.06E-14mmHg at 25°C |
| Index of Refraction | 1.707 |
| UNII-5ZFR16F4QQ |
| Sepimostat [INN] |
| Sepimostat |