GSK 626616
Modify Date: 2025-08-24 18:54:29
GSK 626616 structure
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Common Name | GSK 626616 | ||
|---|---|---|---|---|
| CAS Number | 1025821-33-3 | Molecular Weight | 401.269 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 574.8±60.0 °C at 760 mmHg | |
| Molecular Formula | C18H10Cl2N4OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 301.4±32.9 °C | |
Use of GSK 626616GSK-626616 is a potent, orally bioavailable inhibitor of DYRK3 (IC50=0.7 nM). GSK-626616 inhibits other members of the DYRK family (e.g., DYRK1A and DYRK2) with similar potency, which is a potential therapy for the treatment of anemia[1]. |
| Name | GSK-626616 |
|---|---|
| Synonym | More Synonyms |
| Description | GSK-626616 is a potent, orally bioavailable inhibitor of DYRK3 (IC50=0.7 nM). GSK-626616 inhibits other members of the DYRK family (e.g., DYRK1A and DYRK2) with similar potency, which is a potential therapy for the treatment of anemia[1]. |
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| Related Catalog | |
| Target |
IC50: 0.7 nM (DYRK3)[1] |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 574.8±60.0 °C at 760 mmHg |
| Molecular Formula | C18H10Cl2N4OS |
| Molecular Weight | 401.269 |
| Flash Point | 301.4±32.9 °C |
| Exact Mass | 399.995239 |
| LogP | 4.16 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.755 |
| InChIKey | RJPNRXFBYZVRIB-DHDCSXOGSA-N |
| SMILES | O=C1NC(=Nc2c(Cl)cccc2Cl)SC1=Cc1ccc2nccnc2c1 |
| Storage condition | 2-8°C |
| GSK-626616 |
| OKY0RM282V |
| (5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-1,3-thiazol-4(5H)-one |
| 4(5H)-Thiazolone, 2-[(2,6-dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-, (5Z)- |