PCI-33380

Modify Date: 2025-08-26 14:16:39

PCI-33380 structure	Common Name	PCI-33380
	CAS Number	1022899-36-0	Molecular Weight	855.78
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₆H₅₂BF₂N₁₁O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PCI-33380

PCI-33380 is an irreversible Bruton's Tyrosine Kinase (BTK) inhibitor (fluorescent probe).

Name	PCI-33380

Description	PCI-33380 is an irreversible Bruton's Tyrosine Kinase (BTK) inhibitor (fluorescent probe).
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk Research Areas >> Others
Target	BTK[1][2].
References	[1]. Zuo Y, et al. A novel 2,5-diaminopyrimidine-based affinity probe for Bruton's tyrosine kinase. Sci Rep. 2015 Nov 4;5:16136. [2]. Honigberg LA, et al. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80.

Molecular Formula	C₄₆H₅₂BF₂N₁₁O₃
Molecular Weight	855.78
InChIKey	YUGFMNZIROEBNV-YRNVUSSQSA-N
SMILES	Cc1cc(C)n2c1C=C1C=CC(CCC(=O)NCCN3CCN(CC=CC(=O)N4CCCC(n5nc(-c6ccc(Oc7ccccc7)cc6)c6c(N)ncnc65)C4)CC3)=[N+]1[B-]2(F)F
Storage condition	2-8℃

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China
Product Name: PCI-33380?
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China
Product Name: PCI-33380
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DC Chemicals Limited
China
Product Name: PCI-33380
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
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Email: sales@dcchemicals.com

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PCI-33380 suppliers

Price: ￥7060/10 mM * 1 mL in DMSO

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