2-Methylamino-5-chlorobenzophenone

Modify Date: 2024-01-04 06:25:37

2-Methylamino-5-chlorobenzophenone Structure
2-Methylamino-5-chlorobenzophenone structure
Common Name 2-Methylamino-5-chlorobenzophenone
CAS Number 1022-13-5 Molecular Weight 245.71
Density 1.2±0.1 g/cm3 Boiling Point 421.9±35.0 °C at 760 mmHg
Molecular Formula C14H12ClNO Melting Point 93-95 °C(lit.)
MSDS Chinese USA Flash Point 209.0±25.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 2-Methylamino-5-chlorobenzophenone


(5-Chloro-2-(methylamino)phenyl)(phenyl)methanone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 5-Chloro-2-(methylamino)benzophenone
Synonym More Synonyms

 2-Methylamino-5-chlorobenzophenone Biological Activity

Description (5-Chloro-2-(methylamino)phenyl)(phenyl)methanone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro 2-甲氨基-5-氯苯甲酮是二苯甲酮类的分析标准品。1,2,3 2-甲氨基-5-氯苯甲酮是地西泮的代谢物,也被用作合成地西泮的合成中间体。在缴获的依替唑仑样品中发现了它本产品用于研究和法医应用。
References

[1]. Jain, R.Simplified method for simultaneous determination of diazepam and its metabolites in urine by thin-layer chromatography and direct densitometryJ . Chromatogr .615(2)365-368(1993).

[2]. OlguÍn, HJ, GuzmÁn, DC, GarcÍa, EH, et al.Diazepam: Principal indications related with its molecular actions and advantagesDiazepam59-80(2014).

[3]. Downey, C. , O'Donnell, A., McLaughlin, G., et al.An unusual detection of 2-amino-3-(2-chlorobenzoyl)-5-ethylthiophene and 2-methylamino-5-chlorobenzophenone in illicit yellow etizolam tablets marked " 5617" seized in the Republic of Ireland Drug Test. Anal. (2021).

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 421.9±35.0 °C at 760 mmHg
Melting Point 93-95 °C(lit.)
Molecular Formula C14H12ClNO
Molecular Weight 245.71
Flash Point 209.0±25.9 °C
Exact Mass 245.060745
PSA 29.10000
LogP 4.66
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.627
Stability Stable. Incompatible with strong oxidizing agents.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ0414000
CHEMICAL NAME :
Benzophenone, 5-chloro-2-(methylamino)-
CAS REGISTRY NUMBER :
1022-13-5
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C14-H12-Cl-N-O
MOLECULAR WEIGHT :
245.72

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DJ0414000
HS Code 2922399090

 Synthetic Route

 Customs

HS Code 2922399090
Summary 2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles6

More Articles
Determination of hydrazine in pharmaceuticals IV: Hydrazine and benzylhydrazine in isocarboxazid.

J. Pharm. Sci. 74(1) , 105-7, (1985)

A GC procedure for the simultaneous determination of hydrazine and benzylhydrazine in isocarboxazid raw material and tablet formulations has been developed. The method is based on the reaction of benz...

[The preservability of sibazon breakdown products in the cadavers of experimental animals].

Sud. Med. Ekspert. 41(3) , 24-6, (1998)

Cibasone degradation products were measured in corpses of 15 cats poisoned with cibasone in a dose of 750 mg/kg. Cibasone was assessed by semiquantitative method on Silufol UV-254 plates from the cont...

Simplified method for simultaneous determination of diazepam and its metabolites in urine by thin-layer chromatography and direct densitometry.

J. Chromatogr. A. 615(2) , 365-8, (1993)

A direct densitometric method for determination of diazepam and its metabolites in urine was developed. The proposed procedure involves acid hydrolysis of urine specimens, thereby converting diazepam ...

 Synonyms

Ro 5-4365
2-METHYLAMINO-5-CHLORO BENZOPHENONE
Methyl-aMino ketone
2-Methylamino-5-chlorobenzophenone
Benzophenone,2-acetamido-5-chloro
EINECS 213-822-1
Methanone, [5-chloro-2-(methylamino)phenyl]phenyl-
Diazepam,acid hydrolyzed
Diazepam benzophenone
[5-Chloro-2-(methylamino)phenyl](phenyl)methanone
(5-Chloro-2-(methylamino)phenyl)(phenyl)methanone
5-chloro-2-methylaminobenzophenone
TeMazepaM IMpurity A
MFCD00008284
5-Chloro-2-(Methylamino)Benzophenone
Benzophenone, 2-methylamino-5-chloro-
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