Glycerol-13C2

Modify Date: 2024-01-05 20:08:09

Glycerol-13C2 Structure
Glycerol-13C2 structure
Common Name Glycerol-13C2
CAS Number 102088-01-7 Molecular Weight 94.07910
Density 1.288 g/mL at 25ºC Boiling Point 182ºC(lit.)
Molecular Formula C3H8O3 Melting Point 20ºC(lit.)
MSDS Chinese USA Flash Point 320 °F(lit.)

 Use of Glycerol-13C2


Glycerol-13C2 is the 13C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].

 Names

Name 1,2,3-Propanetriol-1,3-13C2
Synonym More Synonyms

 Glycerol-13C2 Biological Activity

Description Glycerol-13C2 is the 13C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Pennings S, et al. Effect of glycerol on the separation of nucleosomes and bent DNA in low ionic strengthpolyacrylamide gel electrophoresis. Nucleic Acids Res. 1992 Dec 25;20(24):6667-72.  

[3]. Yazdani SS, et al. Anaerobic fermentation of glycerol: a path to economic viability for the biofuelsindustry. Curr Opin Biotechnol. 2007 Jun18(3):213-9.  

[4]. Huang ZH, et al. Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure. Eur J Pharmacol. 2000 Oct 20406(3):453-60.  

 Chemical & Physical Properties

Density 1.288 g/mL at 25ºC
Boiling Point 182ºC(lit.)
Melting Point 20ºC(lit.)
Molecular Formula C3H8O3
Molecular Weight 94.07910
Flash Point 320 °F(lit.)
Exact Mass 94.05410
PSA 60.69000
Index of Refraction n20/D 1.474(lit.)

 Safety Information

Hazard Codes Xi
Risk Phrases R36/38
Safety Phrases S26;S36
RIDADR NONH for all modes of transport

 Synonyms

MFCD00083974
Glycerin-1,3-13C2
GLYCEROL-1,3-13C2
GLYCEROL-1 3-13C2
[1,3-13C2]GLYCEROL
propane-1,2,3-triol