IRAK inhibitor 3
Modify Date: 2025-08-26 23:12:14
IRAK inhibitor 3 structure
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Common Name | IRAK inhibitor 3 | ||
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| CAS Number | 1012343-93-9 | Molecular Weight | 439.48800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H21N5O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of IRAK inhibitor 3IRAK inhibitor 3 is an interleukin-1 (IL-I) receptor-associated kinase (IRAK) kinase modulator extracted from patent WO2008030579 A2. |
| Name | 4-[[[3-(3,4-dimethoxyphenyl)imidazo[1,2-b]pyridazin-6-yl]amino]methyl]benzenesulfonamide |
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| Synonym | More Synonyms |
| Description | IRAK inhibitor 3 is an interleukin-1 (IL-I) receptor-associated kinase (IRAK) kinase modulator extracted from patent WO2008030579 A2. |
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| Related Catalog | |
| Target |
IRAK[1] |
| In Vitro | IRAK inhibitor 3 is an IRAK modulator, which can be used for treating an inflammatory condition, cell proliferative disorder, immune disorder[1]. |
| Kinase Assay | 5 μL of a solution of IRAK inhibitor 3 at a concentration of 50 μM or less in 1% (v/v) DMSO is added to the wells of a 96-well area Black Polystyrene plates. The final concentrations in the reaction well are 10 μM ATP, 0.5 μM IRAK4 CH373, 1.6 μM IRAKI peptide, 1 mM MgCl2, 2 mM DTT, 5 mM MnCl2, 0.01 % BSA, and 0.01 % Tween-20. The volume of the reaction is 45 μL. The reaction mixture is incubated at room temperature for 30 minutes and stopped with the addition of 5 μL of 100 mM EDTA[1]. |
| References |
| Molecular Formula | C21H21N5O4S |
|---|---|
| Molecular Weight | 439.48800 |
| Exact Mass | 439.13100 |
| PSA | 132.45000 |
| LogP | 3.87600 |
| InChIKey | UPFVAHVWLNBVSG-UHFFFAOYSA-N |
| SMILES | COc1ccc(-c2cnc3ccc(NCc4ccc(S(N)(=O)=O)cc4)nn23)cc1OC |
| Storage condition | 2-8℃ |
| IRAK inhibitor 3 |
| 4-((3-(3,4-dimethoxyphenyl)imidazo[1,2-b]pyridazin-6-ylamino)methyl)-benzenesulfonamide |
| CS-0605 |