Lenalidomide-5-Br
Modify Date: 2024-01-06 18:58:10
Lenalidomide-5-Br structure
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Common Name | Lenalidomide-5-Br | ||
|---|---|---|---|---|
| CAS Number | 1010100-26-1 | Molecular Weight | 323.14 | |
| Density | 1.688±0.06 g/cm3 | Boiling Point | 587.6±50.0 °C | |
| Molecular Formula | C13H11BrN2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Lenalidomide-5-BrLenalidomide-5-Br is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-5-Br can be connected to the ligand for protein by a linker to form PROTAC[1]. |
| Name | Lenalidomide-5-Br |
|---|---|
| Synonym | More Synonyms |
| Description | Lenalidomide-5-Br is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-5-Br can be connected to the ligand for protein by a linker to form PROTAC[1]. |
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| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Density | 1.688±0.06 g/cm3 |
|---|---|
| Boiling Point | 587.6±50.0 °C |
| Molecular Formula | C13H11BrN2O3 |
| Molecular Weight | 323.14 |
| 3-(5-bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione |