2093387-36-9

2093387-36-9 structure

Name: Lenalidomide-Br
Chemical Name: Lenalidomide-Br
CAS Number: 2093387-36-9
Molecular Formula: C₁₃H₁₁BrN₂O₃
Molecular Weight: 323.14
Catalog: Research Areas Cancer
Create Date: 2019-12-07 19:50:54
Modify Date: 2025-08-24 23:48:43
Lenalidomide-Br (Compound 41) is the Lenalidomide-based ligand. Lenalidomide-Br can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

Name	Lenalidomide-Br

Description	Lenalidomide-Br (Compound 41) is the Lenalidomide-based ligand. Lenalidomide-Br can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Bai L, et al. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 2019 Nov 11;36(5):498-511.e17. [2]. Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481.