MK-2894 (sodium salt)

Modify Date: 2024-01-16 19:48:55

MK-2894 (sodium salt) structure	Common Name	MK-2894 (sodium salt)
	CAS Number	1006036-88-9	Molecular Weight	495.48900
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₁F₃NNaO₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MK-2894 (sodium salt)

MK-2894 sodium salt is a highly potent and selective second generation EP4 antagonist.IC50 value:Target: EP4MK-2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin.

Name	sodium,4-[1-[[2,5-dimethyl-4-[[4-(trifluoromethyl)phenyl]methyl]thiophene-3-carbonyl]amino]cyclopropyl]benzoate
Synonym	More Synonyms

Description	MK-2894 sodium salt is a highly potent and selective second generation EP4 antagonist.IC50 value:Target: EP4MK-2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Inflammation/Immunology
References	[1]. Blouin M, Han Y, Burch J, Farand J, Mellon C, Gaudreault M, Wrona M, Lévesque JF, Denis D, Mathieu MC, Stocco R, Vigneault E, Therien A, Clark P, Rowland S, Xu D, O'Neill G, Ducharme Y, Friesen R. The discovery of 4-{1-[({2,5-dimethyl-4-[4-(trifluorometh

Molecular Formula	C₂₅H₂₁F₃NNaO₃S
Molecular Weight	495.48900
Exact Mass	495.10900
PSA	97.47000
LogP	5.14800
Storage condition	2-8℃

CS-0680

MK-2894 sodium salt||MK2894 (sodium salt)

MK-2894 sodium salt

MK-2894 (sodium salt)

DC Chemicals Limited
China
Product Name: MK-2894 sodium
Price: $228.8/10mg $864.0/50mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-[1-[[[2,5-Dimethyl-4-[[4-(trifluoromethyl)phenyl]methyl]-3-thienyl]carbonyl]amino]cyclopropyl]benzoic acid sodium salt
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Price: $204/5mg

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MK-2894 (sodium salt)

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