MK-2894 structure
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Common Name | MK-2894 | ||
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CAS Number | 1006036-87-8 | Molecular Weight | 473.50700 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C25H22F3NO3S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of MK-2894MK-2894 is a highly potent and selective second generation EP4 antagonist.IC50 value:Target: EP4MK-2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin. |
Name | 4-[1-[[2,5-dimethyl-4-[[4-(trifluoromethyl)phenyl]methyl]thiophene-3-carbonyl]amino]cyclopropyl]benzoic acid |
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Synonym | More Synonyms |
Description | MK-2894 is a highly potent and selective second generation EP4 antagonist.IC50 value:Target: EP4MK-2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin. |
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Related Catalog | |
References |
Molecular Formula | C25H22F3NO3S |
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Molecular Weight | 473.50700 |
Exact Mass | 473.12700 |
PSA | 98.13000 |
LogP | 6.66660 |
Storage condition | 2-8℃ |
MK-2894||MK2894 |
MK-2894 |
4-{1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic acid |
CS-0679 |