MK-2894

Modify Date: 2024-01-09 21:54:20

MK-2894 Structure
MK-2894 structure
Common Name MK-2894
CAS Number 1006036-87-8 Molecular Weight 473.50700
Density N/A Boiling Point N/A
Molecular Formula C25H22F3NO3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MK-2894


MK-2894 is a highly potent and selective second generation EP4 antagonist.IC50 value:Target: EP4MK-2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin.

 Names

Name 4-[1-[[2,5-dimethyl-4-[[4-(trifluoromethyl)phenyl]methyl]thiophene-3-carbonyl]amino]cyclopropyl]benzoic acid
Synonym More Synonyms

 MK-2894 Biological Activity

Description MK-2894 is a highly potent and selective second generation EP4 antagonist.IC50 value:Target: EP4MK-2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin.
Related Catalog
References

[1]. Blouin M, Han Y, Burch J, Farand J, Mellon C, Gaudreault M, Wrona M, Lévesque JF, Denis D, Mathieu MC, Stocco R, Vigneault E, Therien A, Clark P, Rowland S, Xu D, O'Neill G, Ducharme Y, Friesen R. The discovery of 4-{1-[({2,5-dimethyl-4-[4-(trifluorometh

 Chemical & Physical Properties

Molecular Formula C25H22F3NO3S
Molecular Weight 473.50700
Exact Mass 473.12700
PSA 98.13000
LogP 6.66660
Storage condition 2-8℃

 Synonyms

MK-2894||MK2894
MK-2894
4-{1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic acid
CS-0679
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: MK-2894
  • Price: $1100.0/100mg $2200.0/250mg $4400.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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Price: $224/10mM*1mLinDMSO

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