MK-2894
Modify Date: 2025-08-26 12:36:51
MK-2894 structure
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Common Name | MK-2894 | ||
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| CAS Number | 1006036-87-8 | Molecular Weight | 473.50700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H22F3NO3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MK-2894MK-2894 is a highly potent and selective second generation EP4 antagonist.IC50 value:Target: EP4MK-2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin. |
| Name | 4-[1-[[2,5-dimethyl-4-[[4-(trifluoromethyl)phenyl]methyl]thiophene-3-carbonyl]amino]cyclopropyl]benzoic acid |
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| Synonym | More Synonyms |
| Description | MK-2894 is a highly potent and selective second generation EP4 antagonist.IC50 value:Target: EP4MK-2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin. |
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| Related Catalog | |
| References |
| Molecular Formula | C25H22F3NO3S |
|---|---|
| Molecular Weight | 473.50700 |
| Exact Mass | 473.12700 |
| PSA | 98.13000 |
| LogP | 6.66660 |
| InChIKey | QJZQFVRFJCGDKF-UHFFFAOYSA-N |
| SMILES | Cc1sc(C)c(C(=O)NC2(c3ccc(C(=O)O)cc3)CC2)c1Cc1ccc(C(F)(F)F)cc1 |
| Storage condition | 2-8℃ |
| MK-2894||MK2894 |
| MK-2894 |
| 4-{1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic acid |
| CS-0679 |