Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Sarmazenil
Price: Check
Purity: 99.65%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Sarmazenil
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Contact: Ms Wang
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78771-13-8

78771-13-8 structure

78771-13-8 structure

Name: Sarmazenil
Chemical Name: ethyl 7-chloro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
CAS Number: 78771-13-8
Molecular Formula: C₁₅H₁₄ClN₃O₃
Molecular Weight: 319.74300
Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
Create Date: 2018-04-23 08:00:00
Modify Date: 2025-08-22 11:16:38
Sarmazenil is a benzodiazepine receptor antagonist.

Name	ethyl 7-chloro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
Synonyms	Sarmazenilum Sarmazenil sarmazenil[inn] ethyl 7-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate Sarmazenilum [INN-Latin] ethyl 7-chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate

Description	Sarmazenil is a benzodiazepine receptor antagonist.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Signaling Pathways >> Neuronal Signaling >> GABA Receptor Research Areas >> Neurological Disease
Target	Benzodiazepine receptor[1]
References	[1]. Gath I, et al. Electrophysiological aspects of benzodiazepine antagonists, Ro 15-1788 and Ro 15-3505. Br J Clin Pharmacol. 1984 Oct;18(4):541-7.

Density	1.43g/cm3
Boiling Point	554ºC at 760 mmHg
Molecular Formula	C₁₅H₁₄ClN₃O₃
Molecular Weight	319.74300
Flash Point	288.9ºC
Exact Mass	319.07200
PSA	64.43000
LogP	2.22590
Index of Refraction	1.658
Storage condition	2-8℃

865-47-4 structure

865-47-4

814-49-3 structure

814-49-3

78755-99-4 structure

78755-99-4

~%

78771-13-8 structure

78771-13-8

Literature: Hoffman-La Roche Inc. Patent: US4316839 A1, 1982 ;

2999-46-4 structure

2999-46-4

78755-99-4 structure

78755-99-4

~%

78771-13-8 structure

78771-13-8

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291

Precursor 4
865-47-4 814-49-3 78755-99-4 2999-46-4
DownStream 1
122384-14-9

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