Shanghai Nianxing Industrial Co., Ltd
China
Product Name: L-663581
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: L-663581
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

122384-14-9

122384-14-9 structure

122384-14-9 structure

Name: L-663581
Chemical Name: 7-chloro-5-methyl-3-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one
CAS Number: 122384-14-9
Molecular Formula: C₁₇H₁₆ClN₅O₂
Molecular Weight: 357.79400
Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
Create Date: 2016-11-01 15:36:35
Modify Date: 2025-08-27 00:38:49
L-663581 (FG-8205) is an agonist of benzodiazepine receptor, acting as a partial agonist at GABA A receptor[1].

Name	7-chloro-5-methyl-3-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one
Synonyms	[14C]-FG 8205 7-chloro-5,6-dihydro-3-(5-isopropyl-1,2,4-oxadiazol-3-yl)-5-methyl-6-oxo-4H-imidazo<1,5-a><1,4>benzodiazepine FG 8205

Description	L-663581 (FG-8205) is an agonist of benzodiazepine receptor, acting as a partial agonist at GABA A receptor[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
References	[1]. M D Tricklebank, et al. The pharmacological properties of the imidazobenzodiazepine, FG 8205, a novel partial agonist at the benzodiazepine receptor. Br J Pharmacol. 1990 Nov;101(3):753-61.

Density	1.5g/cm3
Boiling Point	624.1ºC at 760mmHg
Molecular Formula	C₁₇H₁₆ClN₅O₂
Molecular Weight	357.79400
Flash Point	331.3ºC
Exact Mass	357.09900
PSA	77.05000
LogP	3.22260
Vapour Pressure	1.7E-15mmHg at 25°C
Index of Refraction	1.719

106937-66-0 structure

106937-66-0

~%

122384-14-9 structure

122384-14-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291

99622-53-4 structure

99622-53-4

~%

122384-14-9 structure

122384-14-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291

84378-33-6 structure

84378-33-6

~%

122384-14-9 structure

122384-14-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291

122384-65-0 structure

122384-65-0

~%

122384-14-9 structure

122384-14-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291

122384-66-1 structure

122384-66-1

78755-99-4 structure

78755-99-4

~%

122384-14-9 structure

122384-14-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291

78771-13-8 structure

78771-13-8

~%

122384-14-9 structure

122384-14-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291

78755-99-4 structure

78755-99-4

~%

122384-14-9 structure

122384-14-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291

Precursor 6
78771-13-8 78755-99-4 106937-66-0 84378-33-6
122384-65-0 122384-66-1
DownStream 0

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