1854-25-7

1854-25-7 structure

Name: 2-Keto-D-Glucose
Chemical Name: D-glucosone
CAS Number: 1854-25-7
Molecular Formula: C₆H₁₀O₆
Molecular Weight: 178.14000
Catalog: Biochemical Carbohydrate Monosaccharide
Create Date: 2018-02-20 08:00:00
Modify Date: 2025-08-25 14:12:26
2-Keto-D-Glucose (D-Glucosone) is a key intermediate in a secondary metabolic pathway leading to the antibiotic Cortalcerone. 2-Keto-D-Glucose is also an intermediate in the conversion of D-glucose into D-fructose. 2-Keto-D-Glucose is found in various natural sources, including fungi, algae, and shellfish[1][2].

Name	D-glucosone
Synonyms	Arabino-hexosulose D-arabino-hexosulose Fructosone arabino-Hexos-2-ulose Mannosone 3-deoxyglucosone (3S,4R,5R)-3,4,5,6-tetrahydroxy-2-oxohexanal D-Arabino-hexos-2-ulose 2-Keto-D-glucose 2-Ketoglucose Glucosone

Description	2-Keto-D-Glucose (D-Glucosone) is a key intermediate in a secondary metabolic pathway leading to the antibiotic Cortalcerone. 2-Keto-D-Glucose is also an intermediate in the conversion of D-glucose into D-fructose. 2-Keto-D-Glucose is found in various natural sources, including fungi, algae, and shellfish[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
In Vitro	Pyrroloquinoline quinone-dependent 2-keto-D-glucose (2KG) dehydrogenase (2KGDH) has high specificity for the oxidation of 2-Keto-D-Glucose to 2-keto-D-gluconic acid (2KGA). P. aureofaciens (Pa2KGDH) specifically preferred 2KG as a substrate and oxidized the C-1 position of 2KG, indicating that the enzyme is a 2KGDH[3].
References	[1]. Sun, Lianhong, et al. Engineering galactose oxidase to increase expression level in E. coli, enhance thermostability, and introduce novel activities. Dissertation (Ph.D.), California Institute of Technology. [2]. zawa K, et al. A novel pyrroloquinoline quinone-dependent 2-keto-D-glucose dehydrogenase from Pseudomonas aureofaciens. J Bacteriol. 2015 Apr;197(8):1322-9. [3]. Te-ning E.Liu, et al. Convenient, laboratory procedure for producing solid d-arabino-hexos-2-ulose (d-glucosone). Carbohydrate Research. Volume 113, Issue 1, 16 February 1983, Pages 151-157.

Density	1.574 g/cm3
Boiling Point	481ºC at 760 mmHg
Melting Point	118-120°C
Molecular Formula	C₆H₁₀O₆
Molecular Weight	178.14000
Flash Point	258.8ºC
Exact Mass	178.04800
PSA	115.06000
Vapour Pressure	2.85E-11mmHg at 25°C
Index of Refraction	1.55
Storage condition	Hygroscopic, Store under Inert atmosphere -20°C Freezer

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	24/25
RIDADR	NONH for all modes of transport
HS Code	29144000