- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Ranolazine dihydrochloride
- Price: ￥3228.0/5g ￥928.0/1g
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Ranolazine HCl
- Price: $250.0/100mg $500.0/250mg $1000.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Ranolazine dihydrochloride
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Ranolazine dihydrochloride
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Ranolazine
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
95635-56-6
95635-56-6 structure
- Name: Ranolazine dihydrochloride
- Chemical Name: Ranolazine dihydrochloride
- CAS Number: 95635-56-6
- Molecular Formula: C24H35Cl2N3O4
- Molecular Weight: 500.458
- Catalog: Biochemical Inhibitor Transmembrane Transporters Calcium Channel Inhibitor
- Create Date: 2018-02-16 08:00:00
- Modify Date: 2024-01-02 13:33:20
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Ranolazine(RS-43285) is an antianginal agent with antiarrhythmic properties that achieves its effects via a novel mechanism of action (inhibition of the late phase of the inward sodium current), without affecting heart rate or blood pressure (BP). IC50 value:Target: sodium-dependent calcium channelRanolazine is currently approved for use in chronic angina. The basis for this use is likely related to inhibition of late sodium channels with resultant beneficial downstream effects. Randomized clinical trials have demonstrated an improvement in exercise capacity and reduction in angina episodes with ranolazine.
| Name | Ranolazine dihydrochloride |
|---|---|
| Synonyms |
Ranolazine dihydrochloride
RANOLAZINE HCL MFCD03788770 RANOLAZINE DI HCL Ranolazine (dihydrochloride) N-(2,6-Dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazinyl}acetamide dihydrochloride Ranolazine DiHCI Ranolazine and salt 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-, hydrochloride (1:2) Ranolazine Dihydrocloride Ranolazine 2HCl N-(2,6-Dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide dihydrochloride Ranolazine dihydroch |
| Description | Ranolazine(RS-43285) is an antianginal agent with antiarrhythmic properties that achieves its effects via a novel mechanism of action (inhibition of the late phase of the inward sodium current), without affecting heart rate or blood pressure (BP). IC50 value:Target: sodium-dependent calcium channelRanolazine is currently approved for use in chronic angina. The basis for this use is likely related to inhibition of late sodium channels with resultant beneficial downstream effects. Randomized clinical trials have demonstrated an improvement in exercise capacity and reduction in angina episodes with ranolazine. |
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| Related Catalog | |
| References |
| Boiling Point | 624.1ºC at 760 mmHg |
|---|---|
| Melting Point | 222-229.5ºC(lit.) |
| Molecular Formula | C24H35Cl2N3O4 |
| Molecular Weight | 500.458 |
| Exact Mass | 499.200470 |
| PSA | 74.27000 |
| LogP | 3.86080 |
| Appearance | solid | off-white |
| Storage condition | Desiccate at RT |
| Water Solubility | H2O: 10 mg/mL, soluble |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2942000000 |
| HS Code | 2942000000 |
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