Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Tetramethylthiuram sulfide
Price: ￥318.0/500g ￥108.0/100g
Purity: 97.0%
Stocking Period: 3 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Bis(dimethylthiocarbamyl) sulfide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Rubber Accelerator TMTM-Tetramethyl-thiuram Monosulfide
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

97-74-5

97-74-5 structure

Name: Tetramethylthiuram sulfide
Chemical Name: Bis(Dimethylthiocarbamoyl) Sulfide
CAS Number: 97-74-5
Molecular Formula: C₆H₁₂N₂S₃
Molecular Weight: 208.368
Catalog: Organic raw materials Organic sulfur compound
Create Date: 2018-09-25 18:24:14
Modify Date: 2024-01-02 09:41:14
Tetramethylthiuram monosulfide (TMTM) is an active compound. Tetramethylthiuram monosulfide (TMTM) can be used for the research of rubber and various biochemical studies[1][2].

Name	Bis(Dimethylthiocarbamoyl) Sulfide
Synonyms	Tetramethylthiuram sulfide Trithiodicarbonic diamide, N,N,N',N'-tetramethyl- Sulfide, bis[(dimethylamino)thioxomethyl] EINECS 202-605-7 N,N,N',N'-Tetramethyldicarbonotrithioic diamide Bis(dimethylthiocarbamyl) sulfide MFCD00014870 Bis(dimethylthiocarbamyl) monosulfide TMTM

Description	Tetramethylthiuram monosulfide (TMTM) is an active compound. Tetramethylthiuram monosulfide (TMTM) can be used for the research of rubber and various biochemical studies[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Coleman, et al. Vibrational spectra of thiuram sulfides. Normal coordinate analysis of tetramethylthiuram mono-, di-, and tetrasulfides. Journal of Polymer Science, Polymer Physics Edition.Volume: 12.Issue: 5.Pages: 1001-13.Journal.1974. [2]. Yingtao Sun, et al. Synergistic Effect of Copper Sulfate and Tetramethylthiuram Monosulfide Induced Metal-Coordination Cross-Linking in Nitrile–Butadiene Rubber. 25 April 2021.

Density	1.3±0.1 g/cm3
Boiling Point	260.9±23.0 °C at 760 mmHg
Melting Point	107-111 °C(lit.)
Molecular Formula	C₆H₁₂N₂S₃
Molecular Weight	208.368
Flash Point	111.6±22.6 °C
Exact Mass	208.016251
PSA	95.96000
LogP	0.87
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.641
Water Solubility	insoluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WQ1750000

CHEMICAL NAME :: Sulfide, bis(dimethylthiocarbamoyl)

CAS REGISTRY NUMBER :: 97-74-5

BEILSTEIN REFERENCE NO. :: 1775650

LAST UPDATED :: 199806

DATA ITEMS CITED :: 21

MOLECULAR FORMULA :: C6-H12-N2-S3

MOLECULAR WEIGHT :: 208.38

WISWESSER LINE NOTATION :: 1N1&YUS&SYUS&N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 383 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Nutritional and Gross Metabolic - body temperature decrease

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 818 mg/kg

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - changes in cell count (unspecified)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 850 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 520 mg/kg/4W-I

TOXIC EFFECTS :: Liver - changes in liver weight Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 900 mg/kg

SEX/DURATION :: female 6-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: Micronucleus test

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 100 nmol/L

REFERENCE :: SWEHDO Scandinavian Journal of Work, Environment and Health. (Haartmaninkatu 1, SF-00290 Helsinki, 29, Finland) V.1- 1975- Volume(issue)/page/year: 9(Suppl 2),27,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80220 No. of Facilities: 376 (estimated) No. of Industries: 7 No. of Occupations: 23 No. of Employees: 6032 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80220 No. of Facilities: 803 (estimated) No. of Industries: 18 No. of Occupations: 31 No. of Employees: 40683 (estimated) No. of Female Employees: 5320 (estimated)

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H302-H317-H411
Precautionary Statements	P273-P280
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R22;R43;R51/53
Safety Phrases	S24-S26-S37-S61
RIDADR	UN 3077 9/PG 3
WGK Germany	3
RTECS	WQ1750000
Packaging Group	III
Hazard Class	9
HS Code	3812100000

Precursor 9
16420-13-6 128-04-1 75-15-0 2782-91-4
124-40-3 137-26-8 603-35-0 506-77-4
143-33-9
DownStream 9
1115-06-6 51207-31-9 70648-26-9 542-18-7
4837-38-1 102-08-9 27849-33-8 137-26-8
2782-91-4

HS Code	3812100000

97-74-5	12031-49-1
42495-86-3	37231-03-1
12325-81-4	352-93-2
28930-30-5	12024-10-1
25756-83-6	1308-78-7