22672-77-1

22672-77-1 structure

Name: (S)-Higenamine
Chemical Name: (S)-norcoclaurine
CAS Number: 22672-77-1
Molecular Formula: C₁₆H₁₇NO₃
Molecular Weight: 271.31100
Catalog: Research Areas Others
Create Date: 2016-03-06 19:58:21
Modify Date: 2025-08-27 13:20:57
(S)-Higenamine ((S)-Norcoclaurine) is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS)[1].

Name	(S)-norcoclaurine

Description	(S)-Higenamine ((S)-Norcoclaurine) is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS)[1].
Related Catalog	Research Areas >> Others
In Vitro	The biosynthetic pathway leading to benzylisoquinoline alkaloids originates from the enzyme-catalyzed condensation of dopamine and 4-hydrophenylacetaldehyde to yield (S)-norcoclaurine. Both substrates are secondary metabolites derived from the decarboxylation/hydroxylation/deamination of tyrosine[1].
References	[1]. Minami H, et al. Functional analysis of norcoclaurine synthase in Coptis japonica. J Biol Chem. 2007;282(9):6274‐6282.