20183-47-5

20183-47-5 structure

Name: Tenuifolin
Chemical Name: (2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,2 8-dioic acid
CAS Number: 20183-47-5
Molecular Formula: C₃₆H₅₆O₁₂
Molecular Weight: 680.823
Catalog: Biochemical Plant extracts
Create Date: 2018-08-12 16:42:33
Modify Date: 2025-08-24 17:11:39
Tenuifolin is a triterpene isolated from Polygala tenuifolia Willd, has neuroprotective effects. Tenuifolin reduces Aβ secretion by inhibiting β-secretase. Tenuifolin improves learning and memory in aged mice by decreasing AChE activity and has the potential for Alzheimer’s disease (AD) treatment[1].

Name	(2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,2 8-dioic acid
Synonyms	(2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-24,28-dioic acid Olean-12-ene-23,28-dioic acid, 3-(β-D-glucopyranosyloxy)-2,27-dihydroxy-, (2β,3β)- Tenuifolin Olean-12-ene-24,28-dioic acid, 3-(β-D-glucopyranosyloxy)-2,27-dihydroxy-, (2β,3β)- (2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,28-dioic acid

Description	Tenuifolin is a triterpene isolated from Polygala tenuifolia Willd, has neuroprotective effects. Tenuifolin reduces Aβ secretion by inhibiting β-secretase. Tenuifolin improves learning and memory in aged mice by decreasing AChE activity and has the potential for Alzheimer’s disease (AD) treatment[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Beta-secretase Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	IC50: β-secretase; ACHE[1]
References	[1]. Ki-Yeol Yoo, et al. Terpenoids as Potential Anti-Alzheimer’s Disease Therapeutics. Molecules 2012, 17(3), 3524-3538

Safety Phrases	24/25
HS Code	29389090

82410-35-3

20329-98-0

20183-47-5

Literature: Chemical and Pharmaceutical Bulletin, , vol. 30, # 3 p. 810 - 821

82410-33-1

943-89-5

20183-47-5

Literature: Chemical and Pharmaceutical Bulletin, , vol. 30, # 3 p. 810 - 821

Precursor 2
82410-35-3 82410-33-1
DownStream 0